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Valiant Co Ltd crp
Crp, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 94/100, based on 48 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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crp - by Bioz Stars, 2026-03
94/100 stars

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CL-E inhibits IL-6-induced expression of <t>CRP</t> and SOCS3 mRNA in Hep3B cells. Hep3B cells were pretreated with CL-E at concentrations of 10, 30, and 60 µg/ml for 1 h, followed by IL-6 stimulation (10 ng/ml) for 6 h. Total RNA was extracted, and the mRNA levels of (A) CRP and (B) SOCS3 were measured using quantitative real-time PCR. Gene expression levels were normalized to 18S rRNA and are presented as fold change relative to the untreated control. Data represent the mean ± SE (n≥3). * P<0.05, ** P<0.01 and *** P<0.001 vs. the IL-6-treated group; ### P<0.001. CL-E, Curcuma longa L. extract; IL-6, interleukin 6; CRP, C reactive protein; P-, phosphorylated; SOCS3, suppressor of cytokine signaling 3.
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CL-E inhibits IL-6-induced expression of <t>CRP</t> and SOCS3 mRNA in Hep3B cells. Hep3B cells were pretreated with CL-E at concentrations of 10, 30, and 60 µg/ml for 1 h, followed by IL-6 stimulation (10 ng/ml) for 6 h. Total RNA was extracted, and the mRNA levels of (A) CRP and (B) SOCS3 were measured using quantitative real-time PCR. Gene expression levels were normalized to 18S rRNA and are presented as fold change relative to the untreated control. Data represent the mean ± SE (n≥3). * P<0.05, ** P<0.01 and *** P<0.001 vs. the IL-6-treated group; ### P<0.001. CL-E, Curcuma longa L. extract; IL-6, interleukin 6; CRP, C reactive protein; P-, phosphorylated; SOCS3, suppressor of cytokine signaling 3.
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CL-E inhibits IL-6-induced expression of <t>CRP</t> and SOCS3 mRNA in Hep3B cells. Hep3B cells were pretreated with CL-E at concentrations of 10, 30, and 60 µg/ml for 1 h, followed by IL-6 stimulation (10 ng/ml) for 6 h. Total RNA was extracted, and the mRNA levels of (A) CRP and (B) SOCS3 were measured using quantitative real-time PCR. Gene expression levels were normalized to 18S rRNA and are presented as fold change relative to the untreated control. Data represent the mean ± SE (n≥3). * P<0.05, ** P<0.01 and *** P<0.001 vs. the IL-6-treated group; ### P<0.001. CL-E, Curcuma longa L. extract; IL-6, interleukin 6; CRP, C reactive protein; P-, phosphorylated; SOCS3, suppressor of cytokine signaling 3.
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CL-E inhibits IL-6-induced expression of <t>CRP</t> and SOCS3 mRNA in Hep3B cells. Hep3B cells were pretreated with CL-E at concentrations of 10, 30, and 60 µg/ml for 1 h, followed by IL-6 stimulation (10 ng/ml) for 6 h. Total RNA was extracted, and the mRNA levels of (A) CRP and (B) SOCS3 were measured using quantitative real-time PCR. Gene expression levels were normalized to 18S rRNA and are presented as fold change relative to the untreated control. Data represent the mean ± SE (n≥3). * P<0.05, ** P<0.01 and *** P<0.001 vs. the IL-6-treated group; ### P<0.001. CL-E, Curcuma longa L. extract; IL-6, interleukin 6; CRP, C reactive protein; P-, phosphorylated; SOCS3, suppressor of cytokine signaling 3.
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CL-E inhibits IL-6-induced expression of CRP and SOCS3 mRNA in Hep3B cells. Hep3B cells were pretreated with CL-E at concentrations of 10, 30, and 60 µg/ml for 1 h, followed by IL-6 stimulation (10 ng/ml) for 6 h. Total RNA was extracted, and the mRNA levels of (A) CRP and (B) SOCS3 were measured using quantitative real-time PCR. Gene expression levels were normalized to 18S rRNA and are presented as fold change relative to the untreated control. Data represent the mean ± SE (n≥3). * P<0.05, ** P<0.01 and *** P<0.001 vs. the IL-6-treated group; ### P<0.001. CL-E, Curcuma longa L. extract; IL-6, interleukin 6; CRP, C reactive protein; P-, phosphorylated; SOCS3, suppressor of cytokine signaling 3.

Journal: Biomedical Reports

Article Title: Ethyl acetate fraction of Curcuma longa leaves suppresses IL-6-induced STAT3 activation via ERK signaling in Hep3B cells

doi: 10.3892/br.2026.2108

Figure Lengend Snippet: CL-E inhibits IL-6-induced expression of CRP and SOCS3 mRNA in Hep3B cells. Hep3B cells were pretreated with CL-E at concentrations of 10, 30, and 60 µg/ml for 1 h, followed by IL-6 stimulation (10 ng/ml) for 6 h. Total RNA was extracted, and the mRNA levels of (A) CRP and (B) SOCS3 were measured using quantitative real-time PCR. Gene expression levels were normalized to 18S rRNA and are presented as fold change relative to the untreated control. Data represent the mean ± SE (n≥3). * P<0.05, ** P<0.01 and *** P<0.001 vs. the IL-6-treated group; ### P<0.001. CL-E, Curcuma longa L. extract; IL-6, interleukin 6; CRP, C reactive protein; P-, phosphorylated; SOCS3, suppressor of cytokine signaling 3.

Article Snippet: TaqMan primers for human CRP (Hs04183452_g1) and SOCS3 (Hs02330328_s1) were obtained from Applied Biosystems.

Techniques: Expressing, Real-time Polymerase Chain Reaction, Gene Expression, Control